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| dysfunctional uterine bleeding ： ウィキペディア英語版 |
dysfunctional uterine bleeding
Dysfunctional uterine bleeding (DUB) is abnormal genital tract bleeding based in the uterus and found in the absence of demonstrable structural or organic pathology. It is usually due to hormonal disturbances: reduced levels of progesterone causes low levels of prostaglandin F2alpha and causes menorrhagia; increased levels of tissue plasminogen activator (TPA) (a fibrinolytic enzyme) leads to more fibrinolysis.
Diagnosis must be made by exclusion, since organic pathology must first be ruled out.
It can be classified as ''ovulatory'' or ''anovulatory'', depending on whether ovulation is occurring or not.
Some sources state that the term implies a hormonal mechanism.〔(【引用サイトリンク】title=Dysfunctional Uterine Bleeding )〕 Use of the term "dysfunctional uterine bleeding" is currently discouraged in favor of the term "abnormal uterine bleeding."
==Types==
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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